Encapsulating, a feasible and promising approach to combat vitamin D deficiency

Esmaeili, Mina and Yekta, Reza and Abedi, Abdol-Samad and Ghanati, Kiandokht and Zamani Derav, Robabe and Houshyarrad, Anahita and Saberi Dehkordi, Zeinab and Ajami, Marjan and Mahmoudzadeh, Maryam (2021) Encapsulating, a feasible and promising approach to combat vitamin D deficiency. Pharmaceutical Sciences. ISSN 1735-403X

[thumbnail of ps-28-194.pdf] Text
ps-28-194.pdf - Published Version

Download (899kB)

Abstract

Vitamin D (VD) deficiency is a significant issue affecting a large population around the world. As its natural sources are limited, people must constantly fortify their VD. Encapsulating VD increases its bioavailability and stability during processing and storage; hence it has promising potential to avoid VD deficiency. This study reviews current methods of VD fortification and encapsulation. Two predominant methods of VD fortification, i.e., biofortification and direct fortification, are advantageous over VD supplementation. However, significant VD losses occur during processing, storage, and passing across the stomach which can be minimized through encapsulation methods, i.e., micro and nanoencapsulation. Moreover, the capsule features like size, wall-to-core ratio, wall material, carrier oil composition, and encapsulation technique significantly affect VD bioavailability. To assess the optimum encapsulation procedures and possible risks in food fortification, comprehensive in vitro and in vivo studies must be conducted. Depending on the staple food products of a specific region, both VD fortification strategies have great potential in different countries. Besides, the risk of VD overdose due to fortifying a single staple food product is higher than fortifying various staple food products.

Item Type: Article
Subjects: South Asian Library > Medical Science
Depositing User: Unnamed user with email support@southasianlibrary.com
Date Deposited: 15 May 2023 06:04
Last Modified: 06 Jul 2024 07:52
URI: http://journal.repositoryarticle.com/id/eprint/824

Actions (login required)

View Item
View Item