Incidence and Susceptibility Pattern of Clinical Isolates of Pseudomonas aeruginosa from Selected Teaching Hospitals in Southwest Nigeria

Despite advances in sanitation facilities and the introduction of various antimicrobial agents with anti-pseudomonal activities, the life-threatening infections caused by Pseudomonas aeruginosa has continue to be hospital infections. This study was aimed to determining the incidence and susceptibility patterns of P. aeruginosa from some teaching hospitals in Southwest, Nigeria. Seventy-seven (77) isolates of Pseudomonas species were obtained from different clinical specimens from three (3) teaching hospitals in southwest, Nigeria. The isolates were re-identified by culturing on cetrimide agar plate and oxidase test was performed on the isolates. Information on the site of isolation, age and gender of the patient were obtained from request forms. Pseudomonas aeruginosa infections is mostly associated with the age range of 30-39 years in male patients and 10-19 years in female patients (P<0.05). The wound swab (29.87%) has the highest rate of P. aeruginosa infections closely followed by ear swab (22.08%). There was a statistical significant increase in the mean diameter of zone of inhibition of ciprofloxacin against P. aeruginosa when compared with other antibacterial agents (F-ratio = 18.798, P< 0.0001). However, P. aeruginosa was absolutely resistant to ceftazidime and augmentin.