Complete Atrioventricular Block Reveals Rare Transthyretin Cardiac Amyloidosis: Case Report

Introduction: Atrioventricular block in the context of cardiac amyloidosis is often the result of amyloid infiltration of the conduction pathways. This degenerative process disrupts the transmission of electrical impulses along conduction fibers, resulting in symptoms such as bradycardia, syncope and even cardiac arrest.

Case Report: This is a case report of transthyretin cardiac amyloidosis in an 81-year-old patient who was admitted to hospital for an episode of syncope with an electrocardiogram showing complete atrioventricular block. Transthoracic echocardiography demonstrated biventricular infiltrative cardiomyopathy and Cardiac MRI confirmed the presence of amyloid deposits on late enhancement sequences after Gadolinium injection

Conclusion: Early diagnosis of cardiac amyloidosis is crucial to improving patient prognosis, and this requires particular attention to the presence of conduction disorders such as AVB. Management includes pacemaker implantation, combined with specific treatment depending on the type of amyloidosis, such as specific transthyretin stabilizers in ATTR cardiac amyloidosis.