Infective Endocarditis Revealing Laubry Pezzi Syndrome: A Rare Case Report

Background: Infective endocarditis is still a frequent, life-threatening condition, despite advances in diagnosis and treatment. It can occur in a healthy heart, but more often in a pathological heart, as the congenital heart disease without surgery, or with a residual shunt or prosthetic material.

Case Report: We report the case of a 24-year-old patient with no particular pathological antecedents, presenting with prolonged fever, asthenia and altered general condition. Cardiac investigation revealed infective endocarditis in Laubry-Pezzi syndrome with perimembranous ventricular septal defect (VSD) and severe aortic leakage. Management consisted of effective antibiotic therapy combined with aortic valve replacement and VSD closure. The outcome was favorable.